ABSTRACT
Se describe el caso clínico de una fémina de 35 años de edad, quien acudió a la consulta de Hematología del Hospital Provincial Docente Clinicoquirúrgico "Saturnino Lora Torres" de Santiago de Cuba, por presentar decaimiento, insomnio, así como sospecha de anemia y trastornos de la coagulación por antecedentes de sangrado intraabdominal, además de sensación de quemazón en las falanges distales de los dedos de las manos. Los resultados de los exámenes efectuados confirmaron la presencia de neoplasia hematológica mieloproliferativa crónica (trombocitemia esencial). Luego del plan terapéutico inicial con hidroxiurea y Aspirina®, se indicó tratamiento con interferón alfa- 2b recombinante, con lo cual las cifras de plaquetas disminuyeron paulatinamente.
The case report of a 35 year-old female who visited the Hematology Department from "Saturnino Lora Torres" Provincial Clinical Surgical Teaching Hospital in Santiago de Cuba, because of weakness, insomnia, as well as anemia suspicion and clotting disorders due to a history of intraabdominal bleeding, besides burning sensation in the distal phalanges of the hand fingers is described. The results of the laboratory tests confirmed the presence of chronic hematologic myeloproliferative neoplasm (essential thrombocythemia). After the initial therapeutic plan with hydroxiurea and Aspirin®, treatment was indicated with recombinant alpha-2b interferon, with which the number of platelets decreased gradually.
ABSTRACT
Se describe el caso clínico de un paciente de 60 años de edad, quien era atendido en su área de salud por presentar síntomas aparentemente banales y palidez cutaneomucosa. Las pruebas hemoquímicas y la hematimetría revelaron pancitopenia severa y proteinemia marcada, por lo cual se realizaron otros exámenes complementarios para comprobar la presencia de gammapatía monoclonal primaria o asociada a algún proceso neoplásico. Se halló macroglobulinemia primaria, de modo que se confirmó la existencia de la enfermedad de Waldenström.
The case report of a 60 year-old patient is described who was assisted in his health area for presenting apparently banal symptoms and mucocutaneous pallor. The hemochemical tests and the hematimetry revealed severe pancytopenia and marked proteinemia, reason why other complementary tests were carried out, to check the presence of primary monoclonal gammapathy or associated with some neoplasic process. Primary macroglobulinemia was found, so the existence of the disease of Waldenström was confirmed.
ABSTRACT
Se describen 3 casos de pacientes con linfoma MALT, diagnosticados, tratados y seguidos en la consulta de hematología del Hospital Provincial Docente Clinicoquirúrgico "Saturnino Lora" de Santiago de Cuba, a la cual fueron remitidos por gastroenterólogos, otorrinolaringólogos y maxilofaciales de la mencionada institución. Uno de los afectados presentaba una masa tumoral gástrica y en nasofaringe, aparecida en diferentes momentos; otro un tumor linfoide en el paladar duro, que recurrió en ganglios infradiafragmáticos; y un tercero un nódulo linfoide en la glándula salival parótida unilateral, con recidiva en ganglios regionales después de haber sido extirpado. Todos experimentaron una buena respuesta clínica al inicio del tratamiento convencional, pero en 2 de ellos se confirmaron reapariciones no locales del proceso morboso.
Three cases of patients with MALT lymphoma are described, who were diagnosed, treated and followed up at the hematology department of "Saturnino Lora" Teaching Provincial Hospital in Santiago de Cuba, to which they were referred by gastroenterologists, otolaryngologists and maxillofacial specialists of that institution. One of those patients presented with a nasopharyngeal and gastric mass, which appeared at different times; another patient had lymphoid tumor of the hard palate, which recurred in infradiaphragmatic lymph nodes; and a third one had a lymphoid node in the unilateral salivary parotid gland with recurrence in regional nodes after having been removed. All experienced a good clinical response at the beginning of conventional treatment, but in 2 of them non-local recurrences of the disease process were confirmed.